发明名称 |
P27 prevents cellular migration |
摘要 |
This invention provides methods of preventing cellular migration and of treating cardiovascular diseases and tumor metastasis by increasing the intracellular concentration of cyclin-dependent kinase inhibitor p27 or C3 exoenzyme or by decreasing the intracellular concentration of Rho-kinase, and methods of identifying chemical compounds for use in such treatments.
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申请公布号 |
US2003013638(A1) |
申请公布日期 |
2003.01.16 |
申请号 |
US20020172027 |
申请日期 |
2002.06.14 |
申请人 |
MARKS ANDREW R.;MARX STEVEN O. |
发明人 |
MARKS ANDREW R.;MARX STEVEN O. |
分类号 |
G01N33/50;A61K31/395;A61K38/43;A61K45/00;A61P9/00;A61P9/10;A61P35/04;A61P43/00;C07K14/47;C12N5/06;C12Q1/02;C12Q1/48;G01N33/15;G01N33/574;(IPC1-7):A61K31/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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