摘要 |
<p>A compound of the formula (I) in which R<SUP>1 </SUP>is -OR<SUP>11</SUP>, -SR<SUP>11</SUP>, -SOR<SUP>11</SUP>, -SO<SUB>2</SUB>R<SUP>11</SUP>, -NHR<SUP>11</SUP>, or -NR<SUP>12</SUP>R<SUP>13 </SUP>, and R<SUP>11</SUP>, R<SUP>12</SUP>, and R<SUP>13 </SUP>are as defined broadly in the text. R<SUP>2 </SUP>is H, C<SUB>1</SUB>-C<SUB>6</SUB>alkyl, carbamoyl, or an ester group. R<SUP>3 </SUP>is thienyl, pyridyl optionally substituted by halogen or C<SUB>1</SUB>-C<SUB>6</SUB>alkoxy; naphthyl optionally substituted by C<SUB>1</SUB>-C<SUB>6</SUB>alkoxy; dioxane fused phenyl; dioxacyclopentane fused phenyl; or optionally substituted phenyl. Y is CH or N. A process for preparing such compounds, pharmaceutical compositions containing such compounds, and a method of treating asthma using them are also disclosed and claimed.</p> |