发明名称 |
Prolactin inhibiting or stimulating compounds to regulate the immune function |
摘要 |
<p>Methods for rectifying or ameliorating abnormal responses of mammalian immune systems is provided. Also provided are methods for modifying normal responses of the mammalian immune system. Further provided is a method for treating a mammal having an immune dysfunction by administering to the mammal a prolactin reducer and/or enhancer at a predetermined time or times during a 24-hour period that results in modification of the mammal's abnormal prolactin profile so that it approaches or conforms to the prolactin profile of a young mammal of the same species, thereby ameliorating said immune dysfunction. Also provided is a method of upregulating or augmenting an immune response in a mammal.</p> |
申请公布号 |
EP1275392(A2) |
申请公布日期 |
2003.01.15 |
申请号 |
EP20020017154 |
申请日期 |
1995.07.07 |
申请人 |
THE GENERAL HOSPITAL DOING BUSINESS AS MASSACHUSETTS GENERAL HOSPITAL;THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURALAND MECHANICAL COLLEGE |
发明人 |
CINCOTTA, ANTHONY H.;MEIR, ALBERT H. |
分类号 |
A61K45/00;A61K31/00;A61K31/135;A61K31/137;A61K31/165;A61K31/166;A61K31/40;A61K31/405;A61K31/415;A61K31/42;A61K31/445;A61K31/4515;A61K31/454;A61K31/475;A61K31/48;A61K31/54;A61K31/5415;A61K31/565;A61K38/22;A61K45/06;A61P29/00;A61P37/02;A61P37/04;A61P37/06;(IPC1-7):A61K31/498 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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