发明名称 |
VITAMIN D DERIVATIVES |
摘要 |
<p>The object of the present invention is to provide a vitamin D derivative exhibiting excellent physiological activity as medicines, in particular as therapeutic agents for skin disease including psoriasis, and having decreased hypercalcemic activity. The present invention provides vitamin D derivatives represented by the general Formula (1): <CHEM> wherein in Formula (1), X is oxygen or sulfur; R1 is hydrogen or Formula (2) <CHEM> R2 is hydrogen or alkyl; R3 and R4 are hydrogen or alkyl or R3 and R4 together form a double bond between the 16- and 17-positions; R5 is hydrogen or -OR13 in which R13 is hydrogen or a protecting group; and R6 is hydrogen or a protecting group.it</p> |
申请公布号 |
EP1275643(A1) |
申请公布日期 |
2003.01.15 |
申请号 |
EP20010921874 |
申请日期 |
2001.04.18 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
KAWASE, AKIRA;SHIMIZU, HITOSHI;SHIMIZU, KAZUKI;EMURA, TAKASHI;KINOSHITA, KAZUTOMO |
分类号 |
A61P17/00;A61P17/06;C07C401/00;C07F7/18;(IPC1-7):C07C401/00;A61K31/593 |
主分类号 |
A61P17/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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