发明名称 |
TLR/CD14 BINDING INHIBITOR |
摘要 |
<p>The present invention provides an anti-CD14 antibody and fragments thereof that have a function of inhibiting the binding between CD14 and Toll Like Receptor (TLR). And also hybridomas producing the antibody or fragments thereof, peptides, method of preparing antibodies, CD14 mutant polypeptide, method of screening medicaments for treating sepsis and pharmaceutical compositions for sepsis were provided.</p> |
申请公布号 |
EP1275713(A1) |
申请公布日期 |
2003.01.15 |
申请号 |
EP20010917790 |
申请日期 |
2001.04.02 |
申请人 |
MOCHIDA PHARMACEUTICAL CO., LTD. |
发明人 |
FURUSAKO, SHOJI;MORI, SADAO;SHIRAKAWA, KAMON;TAKAHASHI, TOMOHIRO |
分类号 |
A61P31/04;A61P43/00;C07K16/28;(IPC1-7):C07K16/28 |
主分类号 |
A61P31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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