发明名称 |
A process for the simultaneous production of artemisinin and essential oil from the plant artemisia annua |
摘要 |
<p>The present invention relates to a novel process for the simultaneous production of essential oil and artemisinic acid optionally converted into artemisinin, from the plant Artemisia annua, comprising the following steps: a) extracting said plant with a non polar organic solvent, thereby obtaining a non polar organic extract; b) partitioning the non polar organic extract between an organic phase and an aqueous phase; c) evaporating the organic phase substantially to dryness thereby obtaining an organic phase residue, and performing a hydro-distillation of the residue preferably admixed with the plant marc yielding said essential oil d) purifying the aqueous phase to yield artemisinic acid; and e) optionally converting artemisinic acid into artemisinin. The present invention also relates both to the use of artemisinin obtained from said process as an anti-malarial drug, as well as the use of the essential oil produced from the process in perfumery, cosmetics, and aromatherapy.</p> |
申请公布号 |
EP0908460(B1) |
申请公布日期 |
2003.01.15 |
申请号 |
EP19970402349 |
申请日期 |
1997.10.06 |
申请人 |
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH |
发明人 |
JAIN, DHARAM CHAND;TANDON, SUDEEP;BHAKUNI, RAJENDRA SINGH;SIDDIQUE, MOHAMMED SHAFIQUE;KAHOL, ATUL PRAKASH;SHARMA, RAM PRAKASH;KUMAR, SUSHIL;BHATTACHARYA, ASISH KUMAR |
分类号 |
C07D493/20;C11B9/02;(IPC1-7):C07D493/20;A61K31/365 |
主分类号 |
C07D493/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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