摘要 |
<p>PROBLEM TO BE SOLVED: To provide a method for reforming a solid in a supercritical medium which facilitates reforms such as change of size and crystal form, dewatering, desolventing and drying of the solid materials of pharmaceuticals, and even enables creation of a new solid state, by making use of the characteristics of the supercritical medium. SOLUTION: In the method for reforming a liquid-coexisting-base solid and a medicamental solution by desolventing in a supercritical medium, an absobent or an adsorbent may exist for the above liquid.</p> |