METASTASIS-ASSOCIATED GENES

摘要

PURPOSE: Provided are genes which are identified as being metastasis associated. Identifying and profiling of these genes expression can be used to evaluate a sample, to diagnose tumor invasive potential or metastatic development in a sample, or screen for a test compound useful in the prevention or treatment of tumor metastasis. CONSTITUTION: A method for evaluating a sample comprises: determining the abundance of at least one nucleic acid selected from Group I and/or II in a first sample; determining the abundance of the at least one nucleic acid in a second sample that comprises normal cells or tumor cells; comparing the abundance of the at least one nucleic acid in the first sample to the abundance of the at least one nucleic acid in the second sample; and categorizing the sample as having tumor invasive or metastatic potential based on results of the comparing.