发明名称 |
<Beta>3 adrenergiske agonister |
摘要 |
<p>The present invention relates to a beta3 adrenergic receptor agonist of formula (I) or a pharmaceutical salt thereof, which is capable of increasing lipolysis and energy expenditure in cells and, therefore, is useful for treating Type II diabetes and/or obesity. The compound can also be used to lower triglyceride levels and cholesterol levels or raise high density lipoprotein levels or to decrease gut motility. In addition, the compound can be used to reduced neurogenic inflammation or as an antidepressant agent. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for decreasing gut motility are also disclosed.</p> |
申请公布号 |
NO20030098(A) |
申请公布日期 |
2003.01.09 |
申请号 |
NO20030000098 |
申请日期 |
2003.01.09 |
申请人 |
ELI LILLY AND CO |
发明人 |
EVERS, BRITTA;JESUDASON, CYNTHIA DARSHIN;KARANJAWALA, RUSHAD ERUCH;REMICK, DAVID MICHAEL;RUEHTER, GERD;SALL, DANIEL JON;SCHOTTEN, THEO;SIEGEL, MILES GOODMAN;STENZEL, WOLFGANG;STUCKY, RUSSELL DEAN;WERNER, JOHN ARNOLD |
分类号 |
A61K31/341;A61K31/381;A61K31/42;A61K31/421;A61K31/425;A61K31/4436;A61K31/4439;A61K31/4545;A61K31/496;A61K31/506;A61K31/5377;A61P3/04;A61P3/10;A61P43/00;C07D207/32;C07D207/333;C07D213/30;C07D213/82;C07D213/84;C07D231/12;C07D261/08;C07D263/32;C07D275/02;C07D277/24;C07D303/22;C07D307/42;C07D307/58;C07D333/16;C07D401/12;C07D403/12;C07D405/12;C07D407/12;C07D409/12;C07D409/14;C07D413/12;C07D417/12;(IPC1-7):C07D409/12;A61K31/04 |
主分类号 |
A61K31/341 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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