| 发明名称 |
METHODS FOR PREPARATION AND USE OF 1 alpha ,24(S)-DIHYDROXYVITAMIN D2 |
| 摘要 |
A method of inhibiting the hyperproliferation of malignant or neoplastic cells, comprising treating the cells with an antiproliferative amount of 1-alpha, 24(S)-dihydroxyvitamin D2. The method also includes the co-administration of cyotoxic agents with the 1-alpha, 24(S)-dihydroxyvitamin D2. The figure illustrates the preparative steps for the synthesis of 24-hydroxyvitamin D2.
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| 申请公布号 |
WO03002110(A1) |
申请公布日期 |
2003.01.09 |
| 申请号 |
WO2002US20317 |
申请日期 |
2002.06.26 |
| 申请人 |
BONE CARE INTERNATIONAL, INC. |
发明人 |
BISHOP, CHARLES, W.;KNUTSON, JOYCE, C.;STRUGNELL, STEPHEN, A.;MAZESS, RICHARD, B. |
| 分类号 |
A61K45/00;A61K31/282;A61K31/337;A61K31/4745;A61K31/475;A61K31/513;A61K31/519;A61K31/59;A61K31/592;A61K31/664;A61K31/704;A61K31/7048;A61K31/7076;A61K33/24;A61K45/06;A61P35/00;A61P43/00;C07J9/00;C07J71/00;(IPC1-7):A61K31/045 |
主分类号 |
A61K45/00 |
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