发明名称 Treatment of congestive heart failure
摘要 Combinations of diuretics and vasopressin antagonists are useful to slow and reverse the symptoms and process of congestive heart failure, to increase the excretion of water in the urine, and to decrease the excretion of sodium and potassium ions in urine. Preferred vasopressin antagonists have the formula (I) wherein R and R5 are hydrogen or lower alkyl; R1, R2, and R3 are hydrogen, halo, alkyl, alkoxy, and amino; and R4 is hydrogen or phenyl, and a pharmaceutically acceptable salt thereof
申请公布号 US2003008860(A1) 申请公布日期 2003.01.09
申请号 US20020129892 申请日期 2002.05.09
申请人 BAKKER-ARKEMA REBECCA GUGGEMOS;PRESSLER MILTON LETHAN 发明人 BAKKER-ARKEMA REBECCA GUGGEMOS;PRESSLER MILTON LETHAN
分类号 A61K31/55;A61K31/635;(IPC1-7):A61K31/55;A61K31/34 主分类号 A61K31/55
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