METHODS FOR DIAGNOSING AND TREATING A DISEASE MEDIATED BY DECREASED MMP-2 FUNCTION
摘要
The present invention relates to a method for the prevention or treatment of a disease mediated by decreased MMP-2 function. This may result from an aberrant interaction of molecules that stimulate or inhibit MMP-2 protein synthesis, stability, or function, as well as from mutations in the coding or regulatory regions of the gene encoding MMP-2. The invention also provides a method for identifying a substance useful in this context. It further contemplates a method for diagnosing such a disease.
申请公布号
WO03001983(A2)
申请公布日期
2003.01.09
申请号
WO2002US20694
申请日期
2002.06.28
申请人
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY;MARTIGNETTI, JOHN, ATTILIO;DESNICK, ROBERT, J.