发明名称 |
Method for purifying 5' -protected 2' -deoxypurine nucleosides |
摘要 |
A method for efficiently purifying 5' protected 2'-deoxypurine nucleosides, efficient production of which has previously been difficult. Impurities can be separated by obtaining the 5' protected 2'-deoxypurine nucleoside as an inclusion crystal including a solvent such as that having a nitrile structure in order to purify the 5' protected 2'-deoxypurine nucleoside at a high purity. This invention enables synthesis of highly purified protected deoxypurine nucleosides easily on a large scale, which has previously been performed by column chromatography method.
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申请公布号 |
US2003009028(A1) |
申请公布日期 |
2003.01.09 |
申请号 |
US20020120500 |
申请日期 |
2002.04.12 |
申请人 |
KOMATSU HIRONORI;KOUNO TOSHIYUKI;TSUCHIYA KATSUTOSHI |
发明人 |
KOMATSU HIRONORI;KOUNO TOSHIYUKI;TSUCHIYA KATSUTOSHI |
分类号 |
C07H19/173;C07H1/06;C07H19/16;(IPC1-7):C07H19/20;C07H19/06 |
主分类号 |
C07H19/173 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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