发明名称 |
UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND USE |
摘要 |
The invention concerns novel products of formula (I) wherein: Y represents oxygen or sulphur; Z represents C=CH2, CH-CH3 or CH2; R1 represents hydrogen, morpholinyl or the radical (II) wherein the two nitrogen atoms are linear or form a cyclic radical; X represents carbonyl, alkylene or alkenylene, linear or branched containing not more than 6 carbon atoms optionally oxygen- or sulphur-interrupted; R4, R5 and R6 represent hydrogen, a nitrogen-protecting, alkyl, cycloalkyl, aryl and arylalkyl group optionally substituted; R2 represents alkyl optionally substituted by aryl, heteroaryl or -NR4R5; R3 represents alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl optionally substituted. Said products are all in the form of isomers and the salts as medicines. |
申请公布号 |
WO02059102(A3) |
申请公布日期 |
2003.01.09 |
申请号 |
WO2002FR00279 |
申请日期 |
2002.01.23 |
申请人 |
AVENTIS PHARMA S.A.;DEPREZ, PIERRE;PATEK, MARCEL |
发明人 |
DEPREZ, PIERRE;PATEK, MARCEL |
分类号 |
C07D243/08;A61K31/17;A61K31/175;A61K31/36;A61K31/495;A61K31/496;A61K31/551;A61P1/00;A61P3/14;A61P5/18;A61P9/00;A61P9/12;A61P19/00;A61P19/02;A61P19/08;A61P25/08;A61P25/22;A61P25/24;A61P25/28;A61P29/00;A61P31/00;A61P35/00;A61P37/00;C07C273/18;C07C275/24;C07C275/26;C07C275/28;C07C275/34;C07C275/42;C07D295/12;C07D295/13;C07D295/18;C07D317/58;C07D333/20;C07D407/12 |
主分类号 |
C07D243/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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