发明名称 |
Amphiphilic biodegradable block copolymers and self-assembled polymer aggregates formed from the same in aqueous milieu |
摘要 |
There are provided amphiphilic biodegradable block copolymers comprising polyethylenimine (PEI) as a hydrophilic block and aliphatic polyesters as a hydrophobic block, which can form various size of polymer aggregates and have very low critical micelle concentration, approximately 10-3 g/l in comparison with low-molecular-weight micelle, and self-assembled polymer aggregates formed from the block copolymers in aqueous milieu, which can be applied to solubilization of insoluble drug and a delivery system of proteins, genes or drugs.
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申请公布号 |
US2003009004(A1) |
申请公布日期 |
2003.01.09 |
申请号 |
US20020173728 |
申请日期 |
2002.06.19 |
申请人 |
NAM YOON SUNG;KANG HYUNG SEOK;HAN SANG HOON;CHANG IH SEOP |
发明人 |
NAM YOON SUNG;KANG HYUNG SEOK;HAN SANG HOON;CHANG IH SEOP |
分类号 |
C08J3/16;A61K9/16;A61K9/51;A61K47/34;C08G73/02;C08G81/00;C08L53/00;C08L101/16;(IPC1-7):C08G63/02 |
主分类号 |
C08J3/16 |
代理机构 |
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代理人 |
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地址 |
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