发明名称 Aqueous pharmaceutical composition comprising an active ingredient, highly insoluble in water
摘要 <p>Aqueous pharmaceutical composition comprising an active ingredient which is highly insoluble in water, dispersed in liposomes, consists in that the active substance is dispersed in lipids under the temperature between 20 to 30 °C, this dispersion is suspended in the aqueous phase, and stays under the room temperature for up to 48 hours, is heated to 30 to 75 °C during 10 to 45 minutes, cooled to -150/-200 °C, filtrated through the membrane with pores with diameter 50 to 400 nm and concurrently any active substance, which is not captured, is removed.</p>
申请公布号 SK282905(B6) 申请公布日期 2003.01.09
申请号 SK19990001111 申请日期 1998.02.12
申请人 AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. 发明人 CAVALLO GIOVANNI;MARCHITTO LEONARDO
分类号 A61K;A61K9/127;A61K31/192;A61K31/415;A61K31/416;A61K47/10;A61K47/12;A61K47/14;A61K47/24;A61K47/26;A61P15/08;(IPC1-7):A61K9/127 主分类号 A61K
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