PAEL RECEPTOR,CELLS AND ANIMAL EXPRESSING PAEL RECEPTOR AND METHOD OF SCREENING REMEDY FOR PARKINSON’S DISEASE

摘要

It is intended to provide a substrate of Parkin, a system for clarifying a factor causative of Parkinson’s disease with the use of the substrate and a method of screening a remedy for Parkinson’s disease by using the same. Animal cells having a DNA encoding human Pael receptor or a DNA carrying its variant integrated therein; a nonhuman mammal having a DNA carrying the above DNA integrated therein; a probe comprising the whole DNA encoding the human Pael receptor or a part thereof; and an antibody specifically recognizing the Pael receptor.