发明名称 |
PENICILLIN CRYSTAL AND PROCESS FOR PRODUCING THE SAME |
摘要 |
<p>The crystal of the invention is the crystal of diphenylmethyl 2-methyl-2-triazolylmethylpenam-3-carboxylate 1,1-dioxide which is stable substantially without decomposition or degradation of properties even when left to stand at a temperature of 5 to 35 DEG C for a period of 1 year. The crystal of the invention can be prepared by adding diphenylmethyl 2-methyl-2-triazolylmethylpenam-3-carboxylate 1,1-dioxide represented by the formula (1) <CHEM> wherein Ph is a phenyl group, in the form of oily substance or in the form of amorphous powder or an organic solvent solution thereof to at least one species selected from alcohols and ketones to crystallize the diphenylmethyl 2-methyl-2-triazolylmethylpenam-3-carboxylate 1,1-dioxide.</p> |
申请公布号 |
EP1273586(A1) |
申请公布日期 |
2003.01.08 |
申请号 |
EP20010955653 |
申请日期 |
2001.08.10 |
申请人 |
OTSUKA CHEMICAL COMPANY, LIMITED;TAIHO PHARMACEUTICAL CO., LTD. |
发明人 |
SHIMABAYASHI, AKIHIRO;KAWAHARA, ICHIRO |
分类号 |
A61P31/04;C07D499/00;C07D499/18;C07D499/44;C07D499/86;C07D499/87;C07D499/897;(IPC1-7):C07D499/87 |
主分类号 |
A61P31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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