| 发明名称 |
Isolated nucleic acids relating to the fkbA gene within the FK-520 polyketide synthase gene cluster |
| 摘要 |
Host cells comprising recombinant vectors encoding the FK-520 polyketide synthase and FK-520 modification enzymes can be used to produce the FK-520 polyketide. Recombinant DNA constructs comprising one or more FK-520 polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variety of different polyketides with application as pharmaceutical and veterinary products.
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| 申请公布号 |
US6503737(B1) |
申请公布日期 |
2003.01.07 |
| 申请号 |
US19990410551 |
申请日期 |
1999.10.01 |
| 申请人 |
KOSAN BIOSCIENCES, INC. |
发明人 |
REEVES CHRISTOPHER;CHU DANIEL;KHOSLA CHAITAN;SANTI DANIEL;WU KAI |
| 分类号 |
C12N15/09;A61K31/436;A61P25/00;A61P37/06;C07D498/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/10;C12N9/12;C12N15/52;C12P17/18;C12P19/32;C12P19/62;(IPC1-7):C12P19/62 |
主分类号 |
C12N15/09 |
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