发明名称 |
Diagnostics and therapy of diseases associated with HHV-8 infections |
摘要 |
The present invention is directed to monoclonal antibodies capable of specifically binding to and recognizing an antigenic determinant (epitope) of the protein kaposin or a derivative therof, hybridoma cell lines producing said monoclonal antibodies, diagnostic systems for the detection of the presence of a kaposin protein or a derivative thereof as well as antibodies directed against the kaposin protein or a derivative thereof, methods for detection of the expression of kaposin protein or a derivative thereof in a biological sample, methods for the detection of antibodies directed against kaposin protein or a derivative thereof, uses of the monoclonal antibodies provided according to the invention and uses of the kaposin protein or a derivative thereof, each in diagnostics and therapy.
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申请公布号 |
US6503513(B2) |
申请公布日期 |
2003.01.07 |
申请号 |
US20010860276 |
申请日期 |
2001.05.16 |
申请人 |
GSF FORSCHUNGSZENTRUM FUER UMWELT UND GESUNDHEIT GMBH |
发明人 |
HAAS JUERGEN;KREMMER ELISABETH;KLICHE STEFANIE |
分类号 |
C12N15/02;A61K31/00;A61K38/00;A61K39/395;A61P31/00;A61P31/22;A61P35/00;A61P37/00;A61P37/04;C07K7/08;C07K14/03;C07K16/08;C07K16/18;C12N5/10;C12N5/20;C12P21/08;G01N33/569;G01N33/577;(IPC1-7):A61K39/245;C12Q1/70;G01N33/53 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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