EFFICIENT METHOD FOR SCREENING PHYSIOLOGICALLY ACTIVE SUBSTANCE BY UTILIZING EXCESSIVE EXPRESSION ASSAY SYSTEM OF YEAST GENE GROUP

摘要

PROBLEM TO BE SOLVED: To provide an efficient method for screening a physiologically active substance useful for the treatment of human diseases such as cancer, allergy by utilizing an excessive expression assay system of yeast gene groups. SOLUTION: This method for screening the physiologically active substance comprises establishing the excessive expression assay system by utilizing the yeast gene groups, and efficiently screening the active substance from cultured liquid of microorganisms and chemical library compounds by utilizing the system. The method also has a characteristic capable of testing the presence or absence of plural activities of the physiologically active substance by performing plural assays in parallel.