发明名称 |
DIAMINE DERIVATIVES |
摘要 |
Compounds represented by the following general formula (1), salts thereof, solvates of the same or N-oxides of the same: Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4 (1) wherein R1 and R2 represent each hydrogen, etc.; Q1 represents optionall y substituted, saturated or unsaturated 5- or 6-membered hydrocarbyl, etc.; Q2 represents a single bond, etc.; Q3 represents the following group; (wherein Q5 represents C1-8 alkylene, etc.); and T0 and T1 represent each carbonyl, etc. These compounds are useful as preventives and/or remedies for brain infarction, cerebral embolism, myocardial infarction, angina, pulmonary infarction, pulmonary embolism, Buerger~s disease, bottom venous thrombosis, disseminated intravascular coagulation, thrombosis following artificial valve/joint replacement, thrombosis and reocclusion following circulation reconstruction, systemic inflammatory responsive syndrome (SIRS), multiple organ dysfunction (MODS), thrombosis in extracorporeal circulation or blood coagulation in collecting blood.
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申请公布号 |
CA2451605(A1) |
申请公布日期 |
2003.01.03 |
申请号 |
CA20022451605 |
申请日期 |
2002.06.20 |
申请人 |
DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
KOBAYASHI, SYOZO;YOSHINO, TOSHIHARU;YOSHIKAWA, KENJI;NAGAMOCHI, MASATOSHI;HAGINOYA, NORIYASU;UOTO, KOUICHI;OHTA, TOSHIHARU;ONO, MAKOTO;KOMORIYA, SATOSHI;MOCHIZUKI, AKIYOSHI;KANNO, HIDEYUKI;NAGATA, TSUTOMU;NAITO, HIROYUKI;NAKAMOTO, YUMI |
分类号 |
C07D401/12;A61K;A61P;A61P7/02;A61P9/00;A61P9/10;A61P29/00;C07D;C07D209/42;C07D401/14;C07D417/12;C07D417/14;C07D487/04;C07D495/04;C07D498/04;C07D513/04;C07D513/14;C07D519/00;C07K5/06;C07K5/08;(IPC1-7):C07D401/12;C07D471/04;A61K31/428;A61K31/429;A61K31/436;A61K31/437;A61K31/443;A61K31/444;A61K31/454;A61K31/470;A61K31/472;A61K31/496;A61K31/501;A61K31/502;A61K31/517;A61K31/519;A61K31/537 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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