| 发明名称 |
SUSTAINED RELEASE FORMULATION |
| 摘要 |
A composition comprises a protein, a polyiol, and a metal. The protein is stabilized by the polyol and the metal, and is protected from denaturing whe n in contact with an organic solvent. The polyol may be a hydrocarbon containi ng two or more hydroxyl groups (-OH) bonded to carbon. The metal may be divalen t.
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| 申请公布号 |
CA2448218(A1) |
申请公布日期 |
2003.01.03 |
| 申请号 |
CA20022448218 |
申请日期 |
2002.06.21 |
| 申请人 |
GENENTECH, INC. |
发明人 |
CLELAND, JEFFREY L.;OKUMU, FRANKLIN |
| 分类号 |
A61K9/10;A61K9/00;A61K38/00;A61K38/18;A61K38/27;A61K38/28;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/26;A61K47/34;A61K47/36;A61P5/06;A61P5/50;(IPC1-7):A61K38/27;A61K33/30 |
主分类号 |
A61K9/10 |
| 代理机构 |
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代理人 |
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