DIAMINE DERIVATIVES

摘要

Compounds represented by the following general formula (1): Q1−Q2−T0−N(R1)−Q3−N(R2)−T1−Q4 (1) wherein R1 and R2 represent each hydrogen, etc.; Q1 represents optionally substituted, saturated or unsaturated 5− or 6−membered cyclic hydrocarbyl, etc.; Q2 represents a single bond, etc.; Q3 represents the following group; (wherein Q5 represents C1−8 alkylene, etc.); and T0 and T represent each carbonyl, etc.; salts thereof, solvates of the same or N−oxides of the same. These compounds are useful as preventives and/or remedies for brain infarction, cerebral embolism, cardiac infarction, angina, pulmonary infarction, pulmonary embolism, Buerger’s disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombosis following artificial flap/joint replacement, thrombosis and re−obstruction following blood flow reconstruction, systemic inflammatory reaction syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombosis during external circulation or blood coagulation during blood collection.