发明名称 SYSTEM AND METHOD FOR THE LARGE SCALE LABELING OF COMPOUNDS WITH RADIOHALOGENS
摘要 The invention relates to a new method for producing radio-halogenated compounds having very high specific radioactivity. The method improves the stability of the radio-labeled compound such that its biological and/or chemical activity is retained. The main aspect of the invention is that vitamin C and/or ethanol is added to the radiolabeled compound at either or both of just following attachment of the radio-halogen and during purification of the radio-halogenated compound from the labeling mixture, or during packaging for storage.
申请公布号 WO03000271(A2) 申请公布日期 2003.01.03
申请号 WO2002CA00948 申请日期 2002.06.25
申请人 THE UNIVERSITY OF ALBERTA, THE UNIVERSITY OF BRITISH COLUMBIA, CARLETON UNIVERSITY, SIMON FRASER UNIVERSITY AND THE UNIVERSITY OF VICTORIA, COLLECTIVELY DOING BUSINESS AS TRIUMF 发明人 LU, JIANMING
分类号 C07H19/073;A61K51/04;C07H19/06;C07J1/00;C07J7/00;C07K1/13;C07K16/26;G01N33/534 主分类号 C07H19/073
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