发明名称 TGF−ßSUPERFAMILY PRODUCTION/SECRETION PROMOTER
摘要 A TGF−ß superfamily production/secretion promoter containing a compound which is represented by the formula (I) (wherein R<sp>1</sp> represents halogeno, an optionally substituted heterocyclic group, optionally substituted hydroxy, optionally substituted thiol, or optionally substituted amino; A represents optionally substituted acyl, an optionally substituted heterocyclic group, optionally substituted hydroxy, or optionally esterified or amidated carboxyl; B represents an optionally substituted aromatic group; X represents oxygen, sulfur, or optionally substituted nitrogen; and Y represents a divalent hydrocarbon group or heterocyclic group) or containing a salt or prodrug of the compound. The promoter is useful as a preventive/remedy for autonomic neuropathy, bladder function disorders, auditory disorders, bone diseases, etc.
申请公布号 WO03000257(A1) 申请公布日期 2003.01.03
申请号 WO2002JP06350 申请日期 2002.06.25
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD.;SUGIYAMA, YASUO;HAZAMA, MASATOSHI;SHINTANI, ASAE 发明人 SUGIYAMA, YASUO;HAZAMA, MASATOSHI;SHINTANI, ASAE
分类号 A61K31/422;A61P13/10;A61P19/08;A61P25/02;A61P27/16;A61P43/00;(IPC1-7):A61K31/422;A61K45/00 主分类号 A61K31/422
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