| 发明名称 |
AMINO NICOTINATE DERIVATIVES AS GLUCOKINASE (GLK) MODULATORS |
| 摘要 |
The invention related to novel compounds of Formula (I) or a salt, solvate o r prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, useful in the treatment of a (A chemical formula should be inserted here - please see paper copy enclosed) Formula (I) disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinas e.
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| 申请公布号 |
CA2451249(A1) |
申请公布日期 |
2003.01.03 |
| 申请号 |
CA20022451249 |
申请日期 |
2002.06.24 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
ALLEN, JOANNE VICTORIA;CAULKETT, PETER WILLIAM RODNEY;JOHNSTONE, CRAIG;GASKIN, HAROLD;JONES, CLIFFORD DAVID;JAMES, ROGER;HARGREAVES, RODNEY BRIAN;HAYTER, BARRY RAYMOND;MCKERRECHER, DARREN;CURRIE, GORDON STUART |
| 分类号 |
A61K31/443;A61K31/4436;A61K31/4439;A61K31/455;A61K31/496;A61K31/506;A61K31/5377;A61P3/04;A61P3/10;A61P43/00;C07D213/80;C07D401/12;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14;(IPC1-7):C07D213/80;A61K31/44 |
主分类号 |
A61K31/443 |
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