| 摘要 |
Medical device (10) for insertion into the body of human or veterinary patients, wherein the device comprises a) a working element (12) (e.g. a wire, a guidewire, a tube, a catheter, a cannula, a scope (e.g. rigid or flexible endoscope, laparoscope, sigmoidoscope, cystoscope, etc.) a probe, an apparatus for collecting information from a location within the body (e.g., an electrode, sensor, camera, scope, sample withdrawal apparatus, biopsy or tissue sampling device, etc.) which has an outer surface and b) a continuous or non-continuous coating (20) on the outer surface of the working element. The outer surface of the working element (12) is prepared to create a surface topography (22) which promotes mechanical or frictional engagement of the coating (20) to the working element (12). In some embodiments the coating is a lubricious coating (20), such as a fluorocarbon coating or a hydrogel that becomes lubricious when contacted by a liquid. In some embodiments, the coating (20) may expand or swell. Also disclosed are methods for manufacturing such device. |
