发明名称 |
BLOCK COPOLYMER REDUCED IN IMPURITY CONTENT, POLYMERIC CARRIER, PHARMACEUTICAL PREPARATIONS IN POLYMERIC FORM AND PROCESS FOR THE PREPARATION OF THE SAME |
摘要 |
A process for purification which permits satisfactory removal of impurities from a block copolymer consisting essentially of polyethylene glycol and poly(acidic amino acid) and is suitable for the production of a polymeric carrier having a pharmaceutically acceptable purity; a process for producing such a polymeric carrier; a block copolymer reduced in impurity content; a polymeric carrier as described above; pharmaceutical preparations in polymer ic form, produced by the use of the carrier; and a method of subjecting polyethylene glycol and poly(acidic amino acid)- which are impurities contained in the block copolymer- to treatment with either an ion-exchange resin or a partition/adsorption resin and then determining the quantities of them with a gel filtration column.
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申请公布号 |
CA2450448(A1) |
申请公布日期 |
2003.01.03 |
申请号 |
CA20022450448 |
申请日期 |
2002.06.19 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA;SAKURAI, YASUHISA;JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
NAKANISHI, TAKESHI;FUKUSHIMA, SHIGETO;SUZUKI, MASANOBU;MACHIDA, MEGUMI;UEHARA, RYUJI;AKUTSU, TOMOKO;SHIMIZU, KAZUHISA |
分类号 |
C08G69/40;A61K31/704;A61K47/48;A61P35/00;(IPC1-7):C08G69/40;C08G73/10 |
主分类号 |
C08G69/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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