Cosmetic or dermatological composition comprising acylaminoamide derivatives

摘要

Cosmetic and dermatological compositions, comprise an association of an N-acylaminoamide elastase inhibitor (I), together with a muscle relaxant. Cosmetic and dermatological compositions, comprise an association of an N-acylaminoamide elastase inhibitor of formula (I), their salts with acids, optical isomers and racemic mixtures, together with a muscle relaxant. Y = O or S; R1 = H, 1-18C hydrocarbon that may be straight, branched or cyclic (optionally substituted by 1 - 5 groups selected from -OH, -OR, -OCOR, -SH, -SR, -SCOR, -NH2, -NRR', -NHCOR, halo, -CN, -COOR, -COR, -P(O)(OR)2, and -SO2R), -OR, -NH2, -NHR, -NRR', -NHCOR, -COOR, or -COR; R and R' = 1-6C hydrocarbon (optionally substituted by halogens) or together with the N atom they form a heterocycle which may contain a further heteroatom (O, N, S) and may be substituted by 1-5 groups selected from -OH, -OR, -OCOR, -SH, -SR, -SCOR, -NH2, -NHR, -NHCOR, halo, -CN, -COOR, and -COR; R2 = 1-18C hydrocarbon (optionally substituted by 1 - 5 groups selected from -OH, -OR, -OCOR, -SH, -SR, -SCOR, -NH2, -NRR', -NHCOR, halo, -CN, -COOR, -COR); R3 = (II) or (III); y = 0 - 5; y' = 1 - 5; A = 1-18C divalent hydrocarbon (optionally substituted by -OH, -OR, -OCOR, -SH, -SR, -SCOR, -NH2, -NRR', -NHCOR, halo, -CN, -COOR, -COR, -NO2, or -SO2R); B = 1-18C hydrocarbon (optionally substituted by -OH, -OR, -OCOR, -SH, -SR, -SCOR, -NH2, -NRR', -NHCOR, halo, -CN, -COOR, -COR, -NO2, or -SO2R); X = -OH, -OR4, -NH2, -NHR4, -NR4R5, -SR4, -COOR4, -COR4; R4 and R5 = 1-6C hydrocarbon (optionally substituted by 1-5 groups selected from -OH, -OR, -OCOR, -SH, -SR, -SCOR, -NH2, -NHR, -NRR', -NHCOR, halo, -CN, -COOR, -COR); NR4R5 = heterocycle (may contain a further heteroatom (O, N, S) and may be substituted by 1-5 groups selected from -OH, -OR, -OCOR, -SH, -SR, -SCOR, -NH2, -NHR, -NHCOR, halo, -CN, -COOR, and -COR).