发明名称 |
Isolation and expression of a gene for a nitrilase from acidovorax facilis 72w |
摘要 |
Recombinant microbial strains are provided that express nitrilase enzyme and are useful as biocatalysts for the hydrolysis of nitrile-containing substrates. The recombinant cells are transformed with a foreign gene isolated from Acidovorax facilis 72W encoding a thermostable nitrilase enzyme that catalyzes the hydrolysis of nitrile-containing substrates to carboxylic acids under mild reaction conditions. The nucleotide sequence of the nitrilase gene and the deduced amino acid sequence encoded by the nitrilase gene are provided. |
申请公布号 |
KR20020097210(A) |
申请公布日期 |
2002.12.31 |
申请号 |
KR20027013062 |
申请日期 |
2002.09.30 |
申请人 |
DU PONT |
发明人 |
FALLON ROBERT;PAYNE MARK;CHAUHAN SARITA;DICOSIMO ROBERT;GAVAGAN JOHN |
分类号 |
C12N15/09;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/78;C12P7/40;C12P13/00;C12P17/10;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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