COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF DEGENERATIVE BRAIN DISEASE, OR ENHANCING LEARNING AND/OR MEMORY CONTAINING PLATYCODI RADIX EXTRACT

摘要

PURPOSE: A pharmaceutical composition containing a Platycodi Radix extract which inhibits the reduction of a cholinergic material in the brain as well as the destruction of a brain cell caused by excessive formation of glutamate as a neurotransmitter of excitability is provided. Because the composition demonstrates an excellent effect on enhancing cognitive function whiling inhibiting destruction of the brain cell, it can be effectively used as a prophylactic and therapeutic agent for degenerative brain disease and a learning and/or memory enhancer. CONSTITUTION: Platycodi Radix is extracted with 5 to 15 times water at 80 to 100deg.C for 1 to 24hr and then filtered. The titled composition contains the Platycodi Radix extract and one or more selected from Rhizoma Ligustici, Gastrodia Rhizoma, Bupleuri Radix, Angelicae Gigantis Radix, Persicae Semen, Cinnamomi Ramulus, Rhei Rhizoma, Glycyrrhizae Radix, Cnidii Rhizoma, Aurantii Nobilis Pericarpium, Alismatis Rhizoma, Coptidis Rhizoma, Scutellariae Radix, Hoelen, Paeonia lactiflora Pall. var., Atractylodis Rhizoma Alba, Cortex Phellodendri or the like.