发明名称 |
METHOD FOR TREATING AIDS, FOR PREVENTING AND TREATING HIV INFECTION OR INHIBITING HIV PROTEASE AND PHARMACEUTICAL COMPOSITION FOR APPLYING SAID METHOD |
摘要 |
The invention relates to a method for treating AIDS, for preventing and treating an HIV infection or for inhibiting HIV protease by administering : (A) a protease inhibiting compound of a structure I or a pharmaceutically acceptable salt and (B) one of the inhibitors of the reverse transcriptase selected from dideoxycytidine (ddC), dideoxyinosine (ddI) and zidovudine (AZT), and to a pharmaceutical composition for applying the method, which comprises the compound of the structure I and any one of the group comprising dideoxycytidine (ddC), dideoxyinosine (ddI) and zidovudine (AZT) and a pharmaceutically acceptable carrier.
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申请公布号 |
RO118000(B1) |
申请公布日期 |
2002.12.30 |
申请号 |
RO19950001690 |
申请日期 |
1994.03.24 |
申请人 |
MERCK & CO, INC, RAHWAY, NEW JERSEY |
发明人 |
VACCA P JOSEPH;GUARE P JAMES;DORSEY D BRUCE;HOLLOWAY M KATHARINE;HUNGATE W RANDALL |
分类号 |
C07D241/04;A61K9/70;A61K31/40;A61K31/401;A61K31/4025;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/495;A61K31/496;A61K31/70;A61K31/7068;A61K31/7072;A61K45/06;A61P31/12;A61P31/18;C07D207/16;C07D211/60;C07D401/06;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D417/12;(IPC1-7):A61K45/06 |
主分类号 |
C07D241/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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