发明名称 |
METHODS FOR CLONING MAMMALS USING REMODELING FACTORS |
摘要 |
Methods and compositions are provided for remodeling nuclear donor material used in nuclear transfer procedures. By exposing donor chromatin to one or more exogenous remodeling factors, the limited ability of mammalian oocytes to remodel the chromatin of differentiated cells, including fetal and live-born somatic cells, can be increased, resulting in dramatically improved cloning efficiencies.
|
申请公布号 |
CA2450652(A1) |
申请公布日期 |
2002.12.27 |
申请号 |
CA20022450652 |
申请日期 |
2002.06.14 |
申请人 |
INFIGEN, INC. |
发明人 |
EILERTSEN, KENNETH;BETTHAUSER, JEFFREY M.;FORSBERG, ERIK J.;LENO, GREGORY H. |
分类号 |
A01K67/027;C12N5/02;C12N15/27;C12N15/873;C12N15/877;(IPC1-7):C12N15/87;A01K67/00;C12N5/00;C12N15/00;C12N15/09;C12N15/63;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|