| 摘要 |
The invention provides a method for mapping a nucleic acid, comprising the steps of: a) preparing a HAPPY mapping panel comprising a plurality of nucleic acid samples derived from a nucleic acid to be mapped; b) labelling the nucleic acids in the mapping panel; c) preparing a plurality of probes which are complementary to marker sequences present in the nucleic acid to be mapped and immobilising the probes on a solid phase; d) bringing one or more members of the mapping panel into contact with each probe, such that the probe hybridises to sequences in the mapping panel which are complementary thereto; and e) removing non-hybridised nucleic acids and detecting hybridisation of mapping panel nucleic acids to the probe. |
