发明名称 |
ANTIMICROBIAL POLYMERIC SURFACES |
摘要 |
Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are disclosed for covalently derivatizing the surfaces of common materials with an antibacterial polycation, e.g., poly(vinyl-N-pyridinium bromide); the first step of the methods involves coating the surface with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner are bactericidal, i.e., they kill on contact up to 99 % of deposited Gram-positive and Gram-negative bacteria, whether deposited through air or water.
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申请公布号 |
WO02085542(A8) |
申请公布日期 |
2002.12.27 |
申请号 |
WO2002US11983 |
申请日期 |
2002.04.16 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;TRUSTEES OF TUFTS COLLEGE |
发明人 |
TILLER, JOERG, C.;LIAO, CHUN-JEN;LEWIS, KIM;KLIBANOV, ALEXANDER, M. |
分类号 |
A01N43/40;A61L27/34;A61L27/54;C08F8/44;(IPC1-7):B05D3/10;B32B27/04;B32B27/08;B32B27/30;B32B27/32;B32B27/34;B32B27/36;C08F283/00;C08F283/02;C08F283/04;C08L39/08;C08L67/03;C08L77/06 |
主分类号 |
A01N43/40 |
代理机构 |
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主权项 |
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地址 |
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