发明名称 |
REGULATION OF NEURONAL FUNCTION THROUGH METABOTROPIC GLUTAMATE RECEPTOR SIGNALING PATHWAYS |
摘要 |
The present invention provides methods and compositions for modulating the activities of metabotropic glutamate receptor intracellular signaling molecules. The present invention provides methods and compositions for modulating the activities of casein kinase I and/or cyclin-dependent kinase 5 in cells or tissues. The present invention provides methods of modulating the function of calcium channels in cells or tissues. The present invention provides methods of treating calcium channel dysfunction. The present invention provides methods of identifying agents that modulate the activities of the metabotropic glutamate receptor intracellular signaling molecules casein kinase I and/or cyclin-dependent kinase 5 for use in such treatments. |
申请公布号 |
WO02102768(A2) |
申请公布日期 |
2002.12.27 |
申请号 |
WO2002US19288 |
申请日期 |
2002.06.18 |
申请人 |
THE ROCKEFELLER UNIVERSITY |
发明人 |
LIU, FENG;NAIRN, ANGUS, C.;GREENGARD, PAUL |
分类号 |
C12N15/09;A61K45/00;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/24;A61P25/28;A61P25/30;A61P25/36;A61P29/00;A61P35/00;A61P43/00;C12N9/12;C12Q1/02;C12Q1/48 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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