摘要 |
<p>A method and device for electronically controlling the spatial location of charged molecules is described. The method disclosed pertains to controlling the spatial location of charged molecules in a reaction unit wherein a plurality of electrodes are placed, wherein the geometry of electrode placement is closed system such as circular, rectangular or diamond-shape. This control extends to the selective isolation of individual species of charged molecules as well as their transport. The invention is useful in molecular biological reactions, such as nucleic acid hybridizations, nucleic acid amplification, sample preparation, antibody/antigen reactions, clinical diagnostics, and biopolymer synthesis.</p> |