发明名称 |
Adeno-associated virus vectors |
摘要 |
The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
|
申请公布号 |
US2002197237(A1) |
申请公布日期 |
2002.12.26 |
申请号 |
US20020054665 |
申请日期 |
2002.01.22 |
申请人 |
UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
ENGELHARDT JOHN F.;DUAN DONGSHENG |
分类号 |
A01K67/027;A61K31/711;A61K48/00;C07H21/04;C07K14/47;C12N5/10;C12N15/00;C12N15/10;C12N15/64;C12N15/861;C12N15/864;(IPC1-7):A61K48/00;C12N7/00 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|