发明名称 |
Single nucleotide polymorphisms associated with interstitial lung disease |
摘要 |
Single nucleotide polymorphisms (SNPs) in the gene encoding surfactant protein C can be used to diagnose interstitial lung disease and to determine whether an individual is predisposed to developing interstitial lung disease. Single-stranded polynucleotides comprising a contiguous series of nucleotides from a mutant allele of a surfactant protein C gene, as well as antibodies which specifically bind to altered forms of surfactant protein C but not to wild-type surfactant protein C, can be used in various methods to detect the presence of disease-associated SNPs.
|
申请公布号 |
US2002197646(A1) |
申请公布日期 |
2002.12.26 |
申请号 |
US20020074247 |
申请日期 |
2002.02.14 |
申请人 |
NOGEE LAWRENCE M.;COLE F. SESSIONS;WHITSETT JEFFREY A.;HAMVAS AARON |
发明人 |
NOGEE LAWRENCE M.;COLE F. SESSIONS;WHITSETT JEFFREY A.;HAMVAS AARON |
分类号 |
C07K16/18;(IPC1-7):G01N33/53;C07K16/00 |
主分类号 |
C07K16/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|