摘要 |
PROBLEM TO BE SOLVED: To obtain a diamine compound useful for the treatment of acquired immune deficiency, cancer, or the like, based on CXCR4 antagonistic action. SOLUTION: The diamine compound is a compound expressed by formula (I) (R<1> and R<2> are each H or an alkyl; A is a (substituted) cyclic group; X is a bond or an alkylene or an alkenylene group bonded to A optionally through a heteroatom; Y is S, O, C(=O)-N(R<15> ) (R<15> is H or a (substituted) alkyl), SO2 -N(R<16> ) (R<16> is H or a (substxtuted) alkyl), C(=O)-O, SO, SO2 , or N(R<17> ) (R<17> is H or a (substituted) alkyl); A-X-Y may form a (substituted) heterocyclic group; (1) is 2-6; (m) is 2-4; and (n) is O-8) (when Y is -N(R<17> ), A is a (substituted) aromatic heterocyclic group) or its salt.
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