| 发明名称 |
NOVEL METHODS FOR TESTING INHIBITORS OF PAIRED HELICAL FILAMENTS AND USES FOR TREATMENT OF ALZHEIMER'S DISEASE |
| 摘要 |
The present invention relates to the use of inhibitors of intracellular polyanions, for example of RNA or polyanionic polypeptides, or derivatives thereof for the prevention or treatment of Alzheimer disease. In addition, the present invention relates to methods for testing inhibitors for their capacity to inhibit PHF formations and to kits useful in carrying out such methods.
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| 申请公布号 |
US2002197737(A1) |
申请公布日期 |
2002.12.26 |
| 申请号 |
US19990319812 |
申请日期 |
1999.09.07 |
| 申请人 |
MANDELKOW ECKHARD;MANDELKOW EVA MARIA;BIERNAT JACEK;FRIEDHOFF PETER |
发明人 |
MANDELKOW ECKHARD;MANDELKOW EVA MARIA;BIERNAT JACEK;FRIEDHOFF PETER |
| 分类号 |
A61K45/00;A61K31/00;A61K31/70;A61K31/7088;A61K38/00;A61K38/17;A61P25/28;C12Q1/02;G01N33/68;(IPC1-7):G01N33/567;G01N33/543;A61K48/00 |
主分类号 |
A61K45/00 |
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