摘要 |
The present invention is directed to particulate drug carriers, such as vesicles, formed from polysaccharide derivatives. A polysaccharide bearing at least one non-ionic hydrophilic group attached to an individual monosaccharide unit is hydrophobised to form a derivative bearing at least one long chain alkyl residue. Particle formation is then induced in the presence of cholesterol. The particles are suited for entrapment or conjugation of pharmaceutically active ingredients.
|