| 发明名称 |
Method for enhancing mutant enzyme activities in lysosomal storage disorders |
| 摘要 |
Method fore enhancing in a mammalian cell the activity of an enzyme associated with a lysosomal storage disorder by administering a competitive inhibitor of the enzyme in an amount effective to enhance the activity of the enzyme Prefcrred compounds for use in the method are imino sugars and related compounds |
| 申请公布号 |
US2002198225(A1) |
申请公布日期 |
2002.12.26 |
| 申请号 |
US20020172604 |
申请日期 |
2002.06.14 |
| 申请人 |
MOUNT SINAI SCHOOL OF MEDICINE |
发明人 |
FAN JIAN-QIANG;ISHII SATOSHI;ASANO NAOKI;DESNICK ROBERT J. |
| 分类号 |
A61K31/445;A61K31/4465;A61K31/7008;A61K31/7042;A61K31/7052;A61K31/706;A61P43/00;C07D207/12;C07D211/46;C07H17/02;C12N9/40;(IPC1-7):A61K31/513 |
主分类号 |
A61K31/445 |
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