System and method for computer-designing optimum oligo-nucleic acid sequences from nucleic acid base sequences, and oligo-nucleic acid array mounted with the designed oligo-nucleic acid sequences

摘要

A computer software program and a method are provided to design an optimum oligo-nucleic acid sequence candidate from a nucleic acid base sequence. The program comprises a first command for receiving and storing a specified tolerance of double-chain bond temperature; a second command for computing the double-chain bond temperature of a partial sequence at each length, as extending the length; and a third command for determining whether or not the double-chain bond temperature computed by the second command falls within the tolerance specified by the first command, and in case it falls within the range, for outputting the partial sequence with the length as an oligo-nucleic acid sequence candidate. Based on the inputted tolerance of double-chain bond temperature, oligo-nucleic acid sequences with various lengths that meet the double-chain bond temperature condition can be obtained. An oligo-nucleic acid array mounted with the designed oligo-nucleic acid sequences is also provided.