发明名称 Pyrrolidine modulators of chemokine receptor activity
摘要 The present invention is directed to pyrrolidine compounds of the formula I:(wherein R1, R2, R3, R4, R5, R6 and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.
申请公布号 US6498161(B1) 申请公布日期 2002.12.24
申请号 US20000543019 申请日期 2000.04.04
申请人 MERCK & CO., INC. 发明人 CALDWELL CHARLES G.;CHAPMAN KEVIN T.;HALE JEFFREY;KIM DOOSEOP;LYNCH CHRISTOPHER;MACCOSS MALCOLM;MILLS SANDER G.;WILLOUGHBY CHRISTOPHER;BERK SCOTT;KIM RONALD M.
分类号 A61P9/10;A61P31/18;A61P37/06;A61P37/08;C07D401/06;C07D401/14;C07D409/14;C07D413/14;C07D417/14;C07D491/10;C07F9/59;C07F9/6558;(IPC1-7):A61K31/165;C07D207/04;C07D207/12;C07D211/04;C07D211/06 主分类号 A61P9/10
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