| 摘要 |
A mass spectrometer comprising a continuous ion source, a first ion trap, an ion mobility spectrometer downstream of the first ion trap, a quadrupole mass filter downstream of the ion mobility spectrometer and an orthogonal time of flight mass analyser comprising a pusher or puller electrode, orthogonal drift region and detector. The ion mobility spectrometer comprises a plurality of electrodes having apertures therein through which ions may be transmitted. In use a DC voltage gradient is maintained across at least a portion of the ion mobility spectrometer and at least some of the electrodes are supplied with an AC or RF voltage. At least some of the electrodes are housed in a vacuum chamber maintained in use at a pressure within the range 0.1-10 mbar. The orthogonal time of flight mass analyser is arranged downstream of the quadrupole mass filter.
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