发明名称 The use of ribozyme treatment for retinal diseases
摘要 A composition comprising a ribozyme that cleaves mRNA encoding a protein associated with a retinal disease, wherein the protein is selected from P23H mutant rod opsin, S334 mutant rod opsin, VEGF, eNOS, and iNOS. Also described is the use of this composition in the manufacture of a medicament for use in the treatment of a retinal disease.
申请公布号 NZ500427(A) 申请公布日期 2002.12.20
申请号 NZ19980500427 申请日期 1998.04.21
申请人 UNIVERSITY OF FLORIDA 发明人 LEWIN, ALFRED S;HAUSWIRTH, WILLIAM W;DRENSER, KIMBERLY
分类号 C12N15/09;A61K31/7105;A61K35/76;A61K38/00;A61K48/00;A61P9/10;A61P27/02;C12N9/00;C12N15/113;(IPC1-7):C12N15/11;A61K31/70;C12N15/86;C07H21/04 主分类号 C12N15/09
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