Novel surfactant copolymers based on methylidene malonate

摘要

Biocompatible copolymers comprising at least one sequence having a hydrophilic character and at least one sequence having a hydrophobic character, wherein the sequence having a hydrophobic character is formed either: 1- from a homopolymer consisting of recurring units of general formula (1) in which R1 represents an alkyl group having 1 to 6 carbon atoms or a (CH2)m-COOR3 group in which m is an integer between 1 and 5 and R3 represents an alkyl group having 1 to 6 carbon atoms; R2 represents an alkyl group having 1 to 6 carbon atoms; and n is an integer between 1 and 5; or 2- from a random copolymer constituted of different recurring units of formula (1) as defined above; or 3- from a random copolymer consisting mainly of units of formula (1) as defined above. The copolymers are useful in treating the surface of materials or biomaterials to prevent adhesion of tissue cultures.