发明名称 Use of nitric oxide scavengers to modulate inflammation and matrix metalloproteinase activity
摘要 The present invention relates to modulating inflammation, or improving hemodynamic function, associated with trauma, such as that caused by surgery, through the administration of metal complexes, such as ruthenium nitric oxide scavengers. Further, the present invention relates to modulating matrix metalloproteinase activity also by administering such metal complexes. Modulation of the trauma or the metalloproteinase activity reduces tissue damage or causes a protective effect against organ damage.
申请公布号 US2002193363(A1) 申请公布日期 2002.12.19
申请号 US20010017764 申请日期 2001.12.07
申请人 BRIDGER GARY J.;FRICKER SIMON P.;ABRAMS MICHAEL J.;MAYERS IRVIN 发明人 BRIDGER GARY J.;FRICKER SIMON P.;ABRAMS MICHAEL J.;MAYERS IRVIN
分类号 A61K31/555;(IPC1-7):A61K31/555;A61K31/28 主分类号 A61K31/555
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